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Title

EVALUATION OF HOMOCYSTEINE LEVELS IN PATIENTS WITH POLYCYSTIC OVARIAN SYNDROME

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 Start Page 168 | End Page 171

Abstract

 Background: To determine the level of plasma homocysteine in patients with POLYCYSTIC OVARY SYNDROME (PCOS) compared with healthy controls.Materials and Methods: In this prospective case-control study on 85 PCOS women and 83 controls matched by body mass index (BMI), homocysteine levels were assessed.Results: The mean level of homocysteine was 16.25 ± 11.94 mmol/L in patients with PCOS and 11.58 ± 3.82 mmol/L in controls (p=0.002). Patients with PCOS had a significantly higher risk for hyperhomocysteinemia compared with BMI-matched control women.Conclusion: These data suggest that homocysteine levels are elevated in the PCOS population. Further studies are needed to characterize this relationship.

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