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Information Journal Paper

Title

CNS DEPRESSANT EFFECT OF THE CRUDE ETHANOLIC EXTRACT OF THE FLOWERING TOPS OF ROSA DAMASCENA

Pages

  171-174

Abstract

 The ethanolic extract of the flowering tops of ROSA DAMASCENA (Rosaceae) was assessed for effect on the CENTRAL NERVOUS SYSTEM (CNS) using a number of neuropharmacological experimental models in mice. The extract produced a dose-dependent reduction of the onset and duration of pentobarbitone-induced hypnosis, reduction of locomotor and exploratory activities in the open field, hole cross tests. At the same dose levels, the extract dose-dependently inhibited acetic acid-induced writhing in mice. These results suggest that the extract possess CNS DEPRESSANT ACTIVITY.

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    APA: Copy

    NYEEM, A.B., ALAM, M.A., AWAL, M.A., MOSTAFA, M., UDDIN, S.J., ISLAM, N., & ROUF, R.. (2006). CNS DEPRESSANT EFFECT OF THE CRUDE ETHANOLIC EXTRACT OF THE FLOWERING TOPS OF ROSA DAMASCENA. IRANIAN JOURNAL OF PHARMACOLOGY AND THERAPEUTICS (IJPT), 5(2), 171-174. SID. https://sid.ir/paper/297118/en

    Vancouver: Copy

    NYEEM A.B., ALAM M.A., AWAL M.A., MOSTAFA M., UDDIN S.J., ISLAM N., ROUF R.. CNS DEPRESSANT EFFECT OF THE CRUDE ETHANOLIC EXTRACT OF THE FLOWERING TOPS OF ROSA DAMASCENA. IRANIAN JOURNAL OF PHARMACOLOGY AND THERAPEUTICS (IJPT)[Internet]. 2006;5(2):171-174. Available from: https://sid.ir/paper/297118/en

    IEEE: Copy

    A.B. NYEEM, M.A. ALAM, M.A. AWAL, M. MOSTAFA, S.J. UDDIN, N. ISLAM, and R. ROUF, “CNS DEPRESSANT EFFECT OF THE CRUDE ETHANOLIC EXTRACT OF THE FLOWERING TOPS OF ROSA DAMASCENA,” IRANIAN JOURNAL OF PHARMACOLOGY AND THERAPEUTICS (IJPT), vol. 5, no. 2, pp. 171–174, 2006, [Online]. Available: https://sid.ir/paper/297118/en

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