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Title

LETTER TO THE EDITOR: EFFECT OF EXPOSURE TO TOBACCO SMOKE ON RESPONSE TO ANTI-TU-MOR NECROSIS FACTOR-ALPHA TREATMENT IN PATIENTS WITH RHEUMA-TOID ARTHRITIS

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 Start Page 396 | End Page 398

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Abstract

 Dear Editor-in-chief: Rheumatoid Arthritis (RA) patients who are ac-tive smokers have high levels of Tumor Necrosis Factor (TNF) and a relatively higher ratio of TNF binding to soluble TNF receptor. Passive smoking may also impact the response of TNF treatment in patients with RA. The objective of this study was to assess the effect of tobacco smoke exposure, both through active and passive smoking, on response to anti-TNF-a agents at 12-month assessment

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