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Title

PROTECTIVE EFFECTS OF BOVINE COLOSTRUM SUPPLEMENTATION ON INDICATORS OF MUSCLE DAMAGE EXERCISE INDUCED IN RAT

Pages

 Start Page 9 | End Page 19

Abstract

 Background and Aim: Previous studies indicated that BOVINE COLOSTRUM (BC) has antioxidant activity, but the beneficial effects of BC on strenuous EXERCISE oxidative damage is remaining unclear. Thus, this study examined the effects of BC on EXERCISE induced muscle damage in RATs.Materials and Methods: Forty-eight male Wistar RATs randomly divided into 6 equal groups as: Group 1 (control), Group 2 (aerobic EXERCISE), Group 3 (anaerobic EXERCISE), Group 4 (supplements without EXERCISE), Group 5 (supplements with aerobic EXERCISE), Group 6 (supplements with anaerobic EXERCISE). After pretreating of BC, the blood sample from each group was taken in order to measure the levels of LACTATE DEHYDROGENASE (LDH) and CREATINE KINASE (CK). The data were analysed by ANOVA and Tukey test and significant level was set at p<0.05.Results: The plasma levels of LDH (P=0.010) and CK (P=0.006) significantly increased in anaerobic EXERCISE group in comparison with control group. There was no significant difference between aerobic EXERCISE group with the control (P=0.86). The mice were supplemented with EXERCISE and anaerobic EXERCISE extreme (Group 6) was significantly lower CK And LDH levels compared to anaerobic EXERCISE group without supplementation (group 3) had (P=0.001). The results revealed that BC pretreatment significantly prevented LDH and CK increasing induced by strenuous EXERCISE oxidative damage in RATs.Conclusion: colostrum supplement due to its antioxidant properties can be considered as a sports supplement and recommended to reduce muscle damage.

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