Journal Paper

Paper Information

video

sound

Persian Version

View:

274

Download:

0

Cites:

Information Journal Paper

Title

THE EFFECTS OF 8 WEEKS INTERVAL ENDURANCE COMBINED TRAINING ON PLASMA TNF-α, IL-10, INSULIN RESISTANCE AND LIPID PROFILE IN BOY ADOLESCENTS

Pages

 Start Page 43 | End Page 54

Abstract

 Background & Aim: Tomor necrosis factor alpha (TNF-a; as a pro-inflammatory cytokine) and interlokin-10 (IL-10; as an anti-inflammatory cytokine) have an important role in the development and the prevention of systemic inflammation and incidence of obesity-induced diseases such as CAD, respectively. The aim of this study was to investigate the effects of 8-week interval endurance combined training (IECT) on plasma TNF-a, IL-10, insulin resistance, and lipid profiles in overweight and obese boy adolescents.Materials and Methods: In this semi-experimental study, 28 healthy overweight and obese boy adolescents (16.93 ± 1.89 yr., 88.07 ± 9.98 kg. and 28.35 ± 2.55 kg/m²) were volunteered and randomly assigned into training (n=13) and control (n=15) groups. Exercise protocol was IECT (8 WK, 4 d/wk, 70 min/d). Blood samples were taken before and after exercise to assess the variables. Serum levels of TNF-a and IL-10 were measured by sandwich ELISA method. T-test and Pearson correlation coefficient was employed. The criterion of statistical significance was set as p<0.05.Results: The results showed after 8 weeks IECT, in exercise group, the level of TNF-a (p=0.32) was decreased and the levels of IL-10 (p=0.53) was increased, but these changes in comparison with control group weren’t significant (p>0.05). Moreover, the amounts of insulin resistance, triglyceride, total cholestrol; low density lipoprotein, low density lipoprotein/high density lipoprotein, total cholesterol/high density lipoprotein, body fat percent, body mass index, and waist circumference were significantly decreased and VO2max significantly increased (p<0.05).Conclusion: It seems that a combination of interval endurance training for 8 weeks can be considered to weight controling, reducing blood lipids and improving aerobic fitness, but to create favorable changes in cytokines, such as TNF-a and IL-10 is not sufficient. Probably, it is more useful with more intensity and volume. To achieve more accurate results, more studies are needed in this area.

Cites

  • No record.
  • References

  • No record.
  • Related Journal Papers

    Related Seminar Papers

  • No record.
  • Related Plans

  • No record.
  • Recommended Workshops






    File Not Exists.