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Title

The study and comparison of phytochemical and antioxidant activity of variousextracts of Dracocephalum moldavica L. in Sistan and Baluchestan province

Pages

 Start Page 86 | End Page 95

Abstract

 Dracocephalum moldavica L. is an annual herb belongs to Lamiaceae family, which hasbeen used to treat of gastrointestinal, liver disorders and headaches. In this study, floweringbranches of plant were collected from the greenhouse of the university of Sistan andBaluchestan in March 2016. The methanol, ethanol, and aqueous extracts of plant were obtainedby using maceration method. The amount of total Phenolic, Flavonoid and Anthocyanin contentswere evaluated by spectrophotometric methods and the Antioxidant activity of the extracts weredetermined by FRAP and DPPH methods. The results were showed that the Phenolic andflavonoid contents different of methanol, ethanol and aqueous extracts were (82. 10, 71. 8and33. 65 mg GAE/g) and (34. 02, 28. 8and1. 02mg QUE/g), respectively. In the evaluationof Antioxidant activity by DPPH, the inhibitory power of methanol, ethanol and aqueous extractswere (11. 60, 34. 93 and 298. 96 μ g/ml) respectively, and (14. 23, 8. 20 and 1. 01 mM Fe2+/ mg)respectively, sample in FRAP assay. The methanol extract of plant had the greatest content ofphenolic (82. 10 mg GAE / g), Flavonoids (34. 02 mg QUE/g) and Anthocyanin(113. 55μ g/g) andAntioxidant activity compared to ethanol and aqueous extracts, especially it also had the greatestDPPH inhibitory power (IC50= 11. 60 μ g/ml).

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