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Title

RELATIONSHIP OF INFLAMMATORY CYTOKINES, OXIDATIVE STRESS AND CELL INJURY INDICES AFTER VITAMIN-MINERAL SUPPLEMENTATION AND STRENUOUS TRAINING IN FEMALE ELITE SWIMMERS

Writers

AZIZI M. | RAZMJU S. | RAJABI H.

Pages

 Start Page 47 | End Page 62

Abstract

 This study is aimed to investigate the relationship of inflammatory cytokines, OXIDATIVE STRESS and CELL INJURY INDICES after VITAMIN-MINERAL supplementation and STRENUOUS TRAINing in female elite swimmers. Materials and Methods: Twenty-four elite female swimmers volunteered to participate in this study and were randomly divided into two groups, the experimental (Vitamin-mineral supplemented) and the control (Placebo) groups. Both groups participated in monthly programs, 3 times a week, for a total of 4 weeks. They swim almost 3.5 to 4 kin/d. swimmers took one pill of vitamin mineral supplements with their food. Blood sampling Vias done before and after the training period to assess inflammatory cytokines such as IL-6 and TNF-a, MDA and muscle injury indices, such as aspartate aminotransferase (AST), creatine kinase (CK), lactate dehydrogenase, and myoglobin. The 100 m crawl records were measured at the beginning and the end of the training period. To analyze data, paired sample t test and independent t test were used. Results: Inflammatory cytokines decreased significantly in the VITAMIN-MINERAL supplemented group, the MDA also decreased, though not significantly, in this group. There was no significant change between the groups. No significant change was observed in swimming performance in either groups. some of the muscle injury indices, namely, CK and AST, decreased significantly in the VITAMIN-MINERAL-supplemented group (p=0.011 and 0.04, respectively). Inter-group comparisons showed a difference only with regard to CK (p=0.021). Conclusion: In conclusion, ROS was found to affect exercise-induced cytokine production, in which VITAMIN-MINERAL supplementation was found to play an effective role in decreasing exercise induced cytokine production.

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