Journal Paper

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Journal: مراقبت های نوین
Year:1393 | Volume:11 | Issue:4
Start Page:283 | End Page:292

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Title

THE IMPACT OF LINEAR SODIUM-ULTRAFILTRATION PROFILING ON HEMODIALYSIS TOLERANCE

Pages

 Start Page 283 | End Page 292

Abstract

 Background and objective: Low blood pressure and muscle cramps are the most common complications of HEMODIALYSIS. These complications during HEMODIALYSIS cause patient intolerance. One approach that has recently been proposed to prevent this complication of dialysis is to change dialysate sodium concentration and remove the velocity of fluid, a procedure called sodium-ultrafiltration profile. The purpose of this study was to investigate the effect of linear sodium-ultrafiltration profile on patients' tolerance during HEMODIALYSIS.Material and Methods: This was a clinical trial with a crossover design in which 30 HEMODIALYSIS patients with inclusion criteria referring to Be’sat HEMODIALYSIS Center in Hamadan were selected. Each of the patients received routine treatment for two sessions (where dialysate sodium concentration of 138 mmol/l remains constant from the first to the last day of dialysis, and ULTRAFILTRATION rate will not change) and two sessions of Profile 1 Na plus profile 1 ULTRAFILTRATION upon the physician’s order (sodium concentration dialysate at the beginning of dialysis was 146 mmol/l which was linearly decreased at the end of dialysis to 138 mmol/l; ULTRAFILTRATION also decreased in an automated and linear manner over dialysis). Data were analyzed in SPSS (version 16) using Paired t-test, ANOVA with repeated measurements, Tukey Post Hoc and Wolcoxon. The significant level was set for P<0.05.Results: The mean age of patients was 50.83±16.71 years, and 53.3% of them were female. The results showed that the incidence of hypotension was significantly lower during linear profiles than the routine approach (P<0.05), while the comfort level was greater. However, there was no significant difference between the incidences of muscle cramps in the two procedures.Conclusion: Given the simplicity, cost-effectiveness, and increased PATIENT TOLERANCE of sodium and ULTRAFILTRATION profiles during dialysis, we recommend using sodium and ULTRAFILTRATION profiles instead of the routine method.

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