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Journal: JOURNAL OF RESEARCH IN DENTAL SCIENCES | Year:1392 | Volume:10 | Issue:1 (35) | Start Page:59 | End Page:64

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Title

SUBMANDIBULAR METASTATIC MELANOMA WITH UNKNOWN ORIGIN. A CASE REPORT

Pages

 Start Page 59 | End Page 64

Abstract

 Introduction: The origin of metastatic MELANOMA is unknown in approximately 5-10% of the patients. Various suggestions have been made for the primary origin of this lesion. In this article, a rare case of metastatic MELANOMA is reported in submandibular area.Case presentation: A 20 year-old woman was referred with a cystic lump in the submandibular area. She reported a pigmented macule on her lip that was completely regressed at the time of clinical evaluation. Excisional biopsy showed the lesion to be Metastatic MELANOMA. The diagnosis was confirmed by Immuno-histochemcial staining for HMB45 and S100 markers. The patient is reported to be free of disease in four-year follow up based on the clinical as well as Para clinical evaluation.Conclusion: Total excision of the solitary lesion is suggested in patients with metastatic MELANOMA with unknown origin and regression of the primary lesion.

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