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Information Journal Paper

Title

COMPARAITIVE STUDIES OF ANTIBACTERIAL ACTIVITY OF EXTRACTSNASTURTIUM OFFICINALEAND CORIANDRUM SATIVUM AGAINST SOME OF PATHOGENIC BACTERIA

Pages

  47-55

Abstract

 Medicinal plants‚ which may have less adverse reactions‚ can be a suitable substitute for chemical drugs. In this comparative studies of ANTIBACTERIAL ACTIVITY of extracts NASTURTIUM OFFICINALE and CORIANDRUM SATIVUM used on Gram-positive (S. aureus and L. monocytogenes) and Gram-negative (S. Typhimurium and E. coli) bacteria. We used CORIANDRUM SATIVUM and NASTURTIUM OFFICINALE ALCOHOLIC EXTRACT this study. First‚ prepared the ALCOHOLIC EXTRACT of the plants. At concentration of 100 mg/ml, 50 mg/ml, 25 mg/ml, 12.5 mg/ml, 6.25 mg/ml, 3.12 mg/ml, 1.56 mg/ml and 0.78 mg/ml and evaluated its antibacterial effect. Well Diffusion and Microtitr Plate for determining the Minimum Bactericidal Concentration and Minimum Inhibitory Concentrations methods were used on Gram-positive (S. aureus and L. monocytogenes) and Gram-negative (S. Typhimurium and E. coli) bacteria. Results showed that ALCOHOLIC EXTRACT of CORIANDRUM SATIVUM have more ANTIBACTERIAL ACTIVITY than alcohol extracts of NASTURTIUM OFFICINALE. Our results also showed that S. aureus and L. monocytogenes had more susceptibility and S. Typhimurium and E_coli were the resistant one. the extracts from CORIANDRUM SATIVUM and NASTURTIUM OFFICINALE had MIC equal to 6.25 mg/ml and MBC equal to 12.5 mg/ml against S. aureus. The ANTIBACTERIAL ACTIVITY of CORIANDRUM SATIVUM and NASTURTIUM OFFICINALE ALCOHOLIC EXTRACT was observed on gram positive bacteria and so may be beneficial in the treatment of infectious diseases.

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