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Journal: JOURNAL OF FOOD TECHNOLOGY AND NUTRITION | Year:1391 | Volume:9 | Issue:2 (34) | Start Page:29 | End Page:36

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Title

THE EFFECT OF KOMBUCHA EXTRACT ON PLASMA LIPOPROTEINS AND LIVER ENZYMES IN MALE WISTAR RATS

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 Start Page 29 | End Page 36

Abstract

 Introduction: Cardiac and blood vessel diseases are major problems in the developed and developing countries. The most important cause of these diseases is atherosclerosis, that high density of plasma lipids is considered the main factor in its appearance and development. The aim of this study was to investigate the effect of KOMBUCHA extract on plasma LIPOPROTEINS, and LIVER ENZYMES in male Wi star RATs.Materials and Methods: Animals were divided into 4 groups: l) Control group which received normal water and food diet.2) Sham group which received water and high fat diet (included: 66.5g carbohydrate, 20.lg fat, and 4.49g protein).3) Experimental group 1 received high fat diet and KOMBUCHA extract.4) Experimental group 2, received food diet and KOMBUCHA extract. The KOMBUCHA extract was poured in a container and was put in access of the animals. The duration of the treatment has been continued for 8 weeks. After weighting, the animals were anesthetized with ether. After treatment for 8 weeks, blood serum was prepared and the concentrations of triglyceride, cholesterol, plasma LIPOPROTEINS and LIVER ENZYMES such as AST and AL T were measured.Results: The results showed that the serum level of cholesterol, LDL, AST and ALT in both experimental groups had no significant decrease as compared with control group, but serum level of HDL had decreased significantly as compared to the control group (p<0.05). On the other hand, serum level of TG in both experimental groups indicated significant decreases as compared to the control group (p<0.001).Conclusion: The use of the KOMBUCHA extract can decrease triglyceride and increase HDL serum. Therefore this extract might be used in treating diseases such as cardiac and blood vessel diseases.

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