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Information Journal Paper

Title

THE EFFECT SWIMMING CHRONIC STRESS ON PLASMA LEPTIN CONCENTRATION IN ADULT MALE RATES

Pages

 Start Page 14 | End Page 18

Abstract

 IntroductionLeptin is a peptide hormone which is primarily secreted by adipose tissue, regulating the body weight, metabolism and reproductive system functioning. Stress activates hypothalamic- pituitary adrenocortical (HPA) axis that is responsible for the maintenance of homeostasis during stress.Recently, it ihas been known that LEPTIN has an important role in these stress responses. Therefore, the purpose of the present investigation was to determine the effect of chronic SWIMMING STRESS on plasma LEPTIN concentratin and evaluate the role of adrenal glands in the level of LEPTIN.Material and methodsSixty adult male rats were enrolled in this experimental study. The rats were randomly assigned to six groups. Adrenaletomy was done in the adrenalectomized groups. Chronic stress was administered by water immersion for seven days (10 min/day).ResultsChronic stress increased and ADRENALECTOMY decreased the plasma LEPTIN level. Stress had no significant effect on the plasma LEPTIN concentration. in the adrenalectomized rats.ConclusionChronic SWIMMING STRESS activates HPA axis and, in turn, HPA activity probably stimulates LEPTIN secretion.

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