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Title

HORMONAL CONTRACEPTION AND THE RISK OF HIV ACQUISITION

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 Start Page 1 | End Page 8

Abstract

 Introduction: More than 100 million women worldwide use hormonal contraceptive, including using DMPA or oral contraceptive. There is particular concern about a putative link between HORMONAL CONTRACEPTION and HIV infection. The aim of this review article was to evaluate the association between HORMONAL CONTRACEPTION use and risk of HIV infection Methods: We were retrieved through a systematic search of electronic databases such as PubMed, Science Direct, Elsevier, BMJ, JAMA by utilizing keywords HIV prevention, HORMONAL CONTRACEPTION, women' s` health, RISK FACTORS and human immunodeficiency virus (HIV). This search conducted for relevant literature published between 1989 and 2013.Finding: An estimated 40 million people live with human immunodeficiency virus (HIV) globally. Most HIV infected human are of reproductive age 15-49 years. Approximately 45% of women using HORMONAL CONTRACEPTIONs. Long term used of Progestin-only Injectable such as DMPA and NETEN, may cause thinning of cervico-vaginal mucosa, it may lead to abrasions that facilitate access of HIV to CD4+target cells in submucosal tissue and increased simian immunodeficiency virus acquisition. Although the clinical significance of this thinning remains uncertain.Conclusions: The data do not support an association between use of oral contraceptives and increased risk of HIV acquisition. Nonetheless, family planning services are an important venue for HIV prevention activities.

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