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Cites:

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Information Journal Paper

Title

Levofloxacin versus ceftriaxone and azithromycin for treating community-acquired pneumonia: a randomized clinical trial study

Pages

  458-465

Abstract

 Background and Objectives: We compared two common antibiotic regimens for the treatment of mild to moderate CAP: levofloxacin versus β,-lactam and macrolide combination,in terms of their efficacy and side effects. Materials and Methods: Patients with mild to moderate CAP were randomized into two groups. Group I received a combi-nation of 1 gram ceftriaxone daily and 500 mg azithromycin daily for 5-7 days. Group II received levofloxacin 750 mg daily for five days. The signs and symptoms, hospitalization length, and the side effects were investigated. Results: There were 77 and 74 patients in groups I and II. The vital signs of group II were significantly better on the 3rd day of admission, except for the temperature (P=0. 09). The O saturation of group II was markedly improved on the 5th day of admission (P=0. 0061). In terms of clinical symptoms and hospitalization length, group II was considerably better. However, the rate of side effects in both groups was similar (P=0. 885). Conclusion: Hospitalized patients with mild to moderate CAP might take more advantage of fluoroquinolone administra-tion. It could improve the patients' signs and symptoms and reduce hospitalization length, compared with the combination of macrolide and cephalosporin, with the same rate of side effects.

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    APA: Copy

    YADEGARYNIA, DAVOOD, TEHRANI, SHABNAM, Maghsoudi Nejad, Fatemeh, Shojaeian, Fatemeh, & KEYVANFAR, AMIRREZA. (2022). Levofloxacin versus ceftriaxone and azithromycin for treating community-acquired pneumonia: a randomized clinical trial study. IRANIAN JOURNAL OF MICROBIOLOGY, 14(4), 458-465. SID. https://sid.ir/paper/1074631/en

    Vancouver: Copy

    YADEGARYNIA DAVOOD, TEHRANI SHABNAM, Maghsoudi Nejad Fatemeh, Shojaeian Fatemeh, KEYVANFAR AMIRREZA. Levofloxacin versus ceftriaxone and azithromycin for treating community-acquired pneumonia: a randomized clinical trial study. IRANIAN JOURNAL OF MICROBIOLOGY[Internet]. 2022;14(4):458-465. Available from: https://sid.ir/paper/1074631/en

    IEEE: Copy

    DAVOOD YADEGARYNIA, SHABNAM TEHRANI, Fatemeh Maghsoudi Nejad, Fatemeh Shojaeian, and AMIRREZA KEYVANFAR, “Levofloxacin versus ceftriaxone and azithromycin for treating community-acquired pneumonia: a randomized clinical trial study,” IRANIAN JOURNAL OF MICROBIOLOGY, vol. 14, no. 4, pp. 458–465, 2022, [Online]. Available: https://sid.ir/paper/1074631/en

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