In this article, the effective factors in staff empoverment through TOPSIS method have been studied and prioritized. For this purpose, the effective factors were investigated by reviewing the literature and the related concepts in empowering. Then in order to identify the effective factors in the statistical population under study, a questionnaire was compiled. The compiled questionnaire was distributed among the research samples in order to select the main variables under study and to collect their views on the selected variables (factors). After determining the main factors, the most effective ones in empowerment were identified through the use of minitab15 and by drawing a partograph. The reliability of the responses was confirmed by revaluation method. The TOPSIS method was used in order to prioritize the identified factors. To do this, the second questionnaire was distributed among the population to study the effect of each factor with regard to the determined indices. after collection and summation of the data, the decision matrix was olotained. Finally, the factors were graded in terms of their weight and importance. The results indicate that education, employing participation system, personnel motivation, submitting authority, performance-based reward, team work, occupational enrichment, and accepting responsibility are respectively effective in empowering the staff.