In order to determine the normal value of total IgE in children, 2103 sera were taken from D- 14 years old males & females at different part of Tehran, the capital of IRAN.
The technique which was used to measure total IgE was ELISA method using monochlenal anti- IgE antibody.
The results of this research indicated that the lower value for IgE was detected in children at birth (`x= 3.53 IU/ ml), while, the highest value was in 10 years old children (`x= 74.63 IU/ ml). Therefore it has been concluded that by increasal of Age, that IgE value will also increase (r= 0.919).
Regardless to the age value, the IgE content in both male and female are same. Concerning the IgE value in 4 years girls was higher (`x= 44.92) than higher value of IgE (`x= 66.42). was recorded in compare to the same age girls (`x= 49.59) (P<0.05).