The use of medicinal plants as antifungal agents has a long history. Some of fungi causes skin diseases including Epidermaphyton floccosum ،Microsporum canis ،Trichophyton mentagrophytes and other dermathophytes.
The aim of this study was investigation antifungal activity of Citrus medica، Origanum vulgare، Coriandrun sativun، Pimpinella anisum، Illicium verum extracts and determination minimum inhibitory concentration (MIC) and Minimum Fungicidal Concentration (MFC) of these extracts.
These plants purchased from Tehran medicinal markets then identified. methanolic, ethyl acetate and n-hexane extracts prepared by maceration method from seeds of C. sativun، P. anisum and I. verum, fruits of C. medica and aerial parts of O. vulgare. The extracts were dried and different dilutions of them prepared and were submitted for fungal growth by agar dilution method.
The study showed methanol was the most suitable solvent for extraction and among tested plants Pimpinella anisum and Illicium verum had maximum antifungal activities.