Paper Information

Title: 

EFFECTS OF AQUEOUS EXTRACT OF SEED OF FOENICULUM VULGAR ON NEUROGENIC AND INFLAMATORY PAIN IN MICE

Type: POSTER
Author(s): TAHERIAN ABAS ALI*,DEHGHANIAN M.,VAFAEI ABAS ALI,JARAHI M.,SADEGHI HASAN
 
 *RESEARCH CENTER OF PHYSIOLOGY, FACULTY OF MEDICINE, SEMNAN UNIVERSITY OF MEDICAL SCIENCES, SEMNAN,I.R., IRAN
 
Name of Seminar: IRANIAN CONGRESS OF PHYSIOLOGY AND PHARMACOLOGY
Type of Seminar:  CONGRESS
Sponsor:  PHYSIOLOGY AND PHARMACOLOGY SOCIETY, MASHHAD UNIVERSITY OF MEDICAL SCIENCE
Date:  2007Volume 18
 
 
Abstract: 

Background: A little of Previous investigation show that the seed of the Foeniculum vulgar (FV) have many medical effects. The aim of this work is assessment the role of Aquinus extract of seed of FV on acute and chronic pain in formalin test in mice
Material and Methods: In this study male albino mice (25-30 gr.) in 6 groups (n=42), were used. FV (100, 200, 500 and 1000 mg/kg) and saline were injected 30 min before formalin test. Indexes of signs were licking and foot elevation for assessment of acute pain (5 min) and chronic pain (15-40 min) after injection of formalin 5% (25µl) in right paw. Findings indicate that FV has analgesia effect in duration of acute and chronic phases in compare with control and saline groups.
Results: In this study results indicated that Fv has analgesic effect on pain in both doses in
acute and chronic phases (P<0.05).
Conclusion: Finding above showed that FV can modulate
acute and chronic pain. Further research is required to determine the mechanisms by which FV has an inhibitory effect on pain sensation.

 
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