Paper Information

Title: 

LATE ONSET COMPLICATION OF CHEMICAL WARFARE AGENTS INJURED PATIENTS

Type: SPEECH
Author(s): SHOHRATI M.,GHANEEI M.,KHOUSHBATEN A.
 
 
 
Name of Seminar: IRANIAN CONGRESS OF TOXICOLOGY
Type of Seminar:  CONGRESS
Sponsor:  SOCIETY OF TOXICOLOGY
Date:  2004Volume 8
 
 
Abstract: 

During Iraq-Iran war of 1890-1988 several chemical warfare agents (CWA) have been used against Iranian soldiers and civilians. According to documented reports, the most common CWA that has been used was nerve agents and mustard gas. Nerve agents mostly have lethal effects and unstable effects on environment and human. Although recently some reports about of chronic muscular weakness and neural system dysfunction due to these agents have been reported, there is no obvious complications but there are some significant late onset complication of mustard gas exposure is to special mechanism that influence cellular DNA. The most significant effects of mustard gas exposure are on respiratory system (lung and respiratory tract), eyes and skin and the severity of injuries depend on concentration of gas and the patients resistant. Chronic pulmonary complication of mustard manifest in different clinical manifestation including chronic bronchitis, pulmonary fibrosis, asthma, bronchiectasis and tracheal stenos is. One of the chronic ophthalmic complications of these agents is keratitis leading to intensive visual acuity reduction which may cause even blindness. Chronic cutaneus complication xerosis, refractory itching, blister formation in warm seasons and hyper and hypo pigmentation of the lesions.
Study on approximately 34000 of the victims has indicated that incidence of chronic pulmonary, ocular and cutaneous lesions of these patients are 42.5%, 39.3% and 24.5% retrospectively. These lesions are categorized to normal, mild, moderate and severe.

 
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