Paper Information

Title: 

STUDY OF ANTI-INFLAMMATORY EFFECTS OF AQUATIC EXTRACTION OF APIUM GRAVEOLENS L. IN MICE

Type: POSTER
Author(s): RAMEZANI M.*,NASRI M.,YASA N.
 
 *DEPT. OF BIOLOGY, ASHTIAN ISLAMIC AZAD UNIVERSITY
 
Name of Seminar: IRANIAN CONGRESS OF PHYSIOLOGY AND PHARMACOLOGY
Type of Seminar:  CONGRESS
Sponsor:  PHYSIOLOGY AND PHARMACOLOGY SOCIETY, MASHHAD UNIVERSITY OF MEDICAL SCIENCE
Date:  2007Volume 18
 
 
Abstract: 

Introduction: On the base of traditionally herbal medicine and our finding of anti-inflammatory effect of hydro alcoholic extract of Apium graveolens L. seeds, in the present study aquatic extract was evaluated to find effective fraction.
Methods: NMRI mice were divided into three groups: positive control (dexamethason 15mg/kg), negative control (normal saline), and experimental groups. Experimental groups were injected by 100,200,300,400 and 500mg/kg of extract. After 15 min xylene-induced ear oedema were used.
Results: Results have shown significant anti-inflammatory effect between extract (200-500mg/kg doses) with control, while there was not significant difference to dexamethason. The most effective doses was 400mg/kg (p<0.001).
Conclusion: These data affirm the traditional Use of this plant for inflammatory condition.

 
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