Click for new scientific resources and news about Corona[COVID-19]

Paper Information

Title: 

ANTI DIABETIC EFFECTS OF OLEA EUROPEA L. FRUIT AQUATIC EXTRACT IN STREPTOZOSIN INDUCED DIABETIC RATS

Type: POSTER
Author(s): ARALEILI S.*,SOULATI J.,MOLA ESMAEIL R.
 
 *DEPT. OF BIOLOGY, ISLAMIC AZAD UNIVERSITY, KAZEROON BRANCH
 
Name of Seminar: IRANIAN CONGRESS OF PHYSIOLOGY AND PHARMACOLOGY
Type of Seminar:  CONGRESS
Sponsor:  PHYSIOLOGY AND PHARMACOLOGY SOCIETY, MASHHAD UNIVERSITY OF MEDICAL SCIENCE
Date:  2007Volume 18
 
 
Abstract: 

Introduction: Diabetes mellitus is one of the most common endocrine metabolic disorders. Considering the high incidence of diabetes mellitus in society and related therapeutic problem, the purpose of this research is investigation of Olea europea L. fruit aquatic extract on serum glucose, insulin, urea, creatinin in stereptozosin-indused diabetic adult male rats.
Methods: Olea europea L. fruits were dried in shadow and aquatic extract was made of it. After water evaporation the obtained extract was dried and made powdered. Powdered extract immediately was supplied as suspension in pure water before gavage. The animals were made diabetic by the i.p injection of streptozosin (i.p 65 mg/kg). Intact and diabetic rats were treated by gavage of suspension extract of Olea fruits (0.2, 0.5 g/ kg). Blood samples of retro-orbital sinus were obtained at zero hour before the gavage of water & Olea fruit aquatic extract and at 1, 3, 5 hours after it. The amount of serum glucose, urea, creatinin was measured by acetone method. The amount of serum insulin was measured by Radio Immunoessi method.
Result: 0.2, 0.5 g/kg doses decreased serum glucose and Urea significantly (P<0.001) at 1, 3, 5 hours after the treatment in comparison to control group.
Conclusion: The results indicate that Olea fruit aquatic extract have a significant decreasing effect on serum glucose, urea in diabetic rats comparing with control group. 

 
Keyword(s): 
 
 
Yearly Visit 49   tarjomyar
 
Latest on Blog
Enter SID Blog