Paper Information

Title: 

COMPARE OF THE EFFECT OF ALOE EXTRACT AND GLIBENCLAMIDE IN CONTROLLING OF SEVERE DIABET TYPE I IN RATS THAT B CELL'S DESTROYED WITH STZ ,COMPLETELY

Type: POSTER
Author(s): DAEMI M.,KHAYATZADEH J.,NIAZMAND S.,HASHEMI Z.,MOEIN A.A.*
 
 *
 
Name of Seminar: IRANIAN CONGRESS OF PHYSIOLOGY AND PHARMACOLOGY
Type of Seminar:  CONGRESS
Sponsor:  PHYSIOLOGY AND PHARMACOLOGY SOCIETY, MASHHAD UNIVERSITY OF MEDICAL SCIENCE
Date:  2007Volume 18
 
 
Abstract: 

Diabet Mellitus is a major endocrine disorder and growing health problem in most of countries .Nowadays, herbal medicine such as aloe extract is used to control Diabet, because the herbs have no or few side effects. This study was been conducted to compare the effect of aloe extract and Glibenclamide in controlling of severe Diabet type I.
Methods: The experiment study performed in 20 Diabetic rats. These rats were been Diabetic by injecting of Streptozocin. After 2 weeks, they were divided in 2 groups (n=10) accidentally and one group treated by 200 mg/kg aloe extract and another by 5mg/kg Glibenclamide, for 4weeks.Then FBS of them were checked. SPSS 13 was used for analysis.
Result: The result showed there was no difference between the mean of FBS in 2groups and both of drugs wasn't effective on control of severe Diabet type I.
Discussion: we found aloe extract and Glibenclamide are ineffective in controlling of severe Diabet type I. Nowadays, Diabet is a major disease, so we suggest, early treatment in Diabet begin to prevent of more damage of Beta cell's .

 
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