Paper Information

Title: 

STUDYING THE EFFECT OF PERITONEUM INJECTION OF SAFFRON EXTRACT ON REDUCING PAIN IN RAT

Type: POSTER
Author(s): AKHOUNDI MEYBODI H.*,BASHARDOUST N.,VAHIDI MEHRJARDI A.R.
 
 *SCIATIC SOCIETY MEDICINE, ISLAMIC AZAD UNIVERSITY, YAZD BRANCH
 
Name of Seminar: IRANIAN CONGRESS OF PHYSIOLOGY AND PHARMACOLOGY
Type of Seminar:  CONGRESS
Sponsor:  PHYSIOLOGY AND PHARMACOLOGY SOCIETY, MASHHAD UNIVERSITY OF MEDICAL SCIENCE
Date:  2007Volume 18
 
 
Abstract: 

Faculty pain is a physiologic response to an irritant stimulus which all people have experienced it. Nowadays, we often use sedative and narcotic drugs, in order to reduce pain. That all have many side effects. In traditional medicine, herbal medicines such as saffron were used for reducing pain. Therefore, we decided to study the anti-pain effect of saffron extract on rat. This study was accomplished on 24 male rats empirically which divided into three groups of six rats with weight 20-25 gram, after extracting from saffron, the extract obtained was produced in 1 and 2 and 4 mm/distilled water dilutions and was injected into group inside peritoneum. After is minutes, we injected 50 micro litter diluted solution with 215% formalin and considered the behavior of rat in every is seconds during one hours. Then we analyzed the data with statistical test A NOVA. From statistical conclusions, we concluded that the injection of diluted saffron extract produce anti-pain effect on reducing chronic and acute pain and suspend the chronic pain period, this anti-pain effect is clearer in 1 millimeter density in too milliliter distilled water. According to public problem of pain in community and relatively great side effects of anti-pain drugs present in medicine market, it is recommended to use saffron for reducing pain in patients with chronic pains and other researches in this case appear to be necessary.

 
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