Paper Information

Title: 

ANALGESIC EFFECT OF METHANOLIC SEED EXTRACTS OF PLANTAGO MAJOR AND P.OVATA IN MALE RAT

Type: POSTER
Author(s): POURABOULI IRAN*,MEHRABANI M.,POURABOULI BATOUL,ABBASNEZHAD M.,MIRTAJ ALDINI S.M.
 
 *DEPT OF BIOLOGY, SCHOOL OF SCIENCE, SHAHEED BAHONAR UNIVERSITY OF KERMAN
 
Name of Seminar: IRANIAN CONGRESS OF PHYSIOLOGY AND PHARMACOLOGY
Type of Seminar:  CONGRESS
Sponsor:  PHYSIOLOGY AND PHARMACOLOGY SOCIETY, MASHHAD UNIVERSITY OF MEDICAL SCIENCE
Date:  2007Volume 18
 
 
Abstract: 

Introduction: There are some reports concerning the analgesic effect of the plants Plantago. major and P.ovata in traditional medicine. In this study we evaluate the possible analgesic effect of these plants through experimental pain models.
Methods: At first methanolic seed extracts of these plants  prepared . Then doses 100, 200 and 300 mg/kg,i.p of them used in male rats 1 hour beforepain evaluation by formalin test..According to this, minuets 0-5 and 16-60 considered as acute and chronic phases of pain respectively.
Results: P.major significantly reduced acute pain (37 and 31 percent) in doses of 200 and 300 mg/kg,i.p but P.ovata  reduced it (12.5 percent ) at 100 mg/kg,i.p and non of them had effect on chronic pain.
Conclusion: Both Plantago (major and ovata) have analgesic effect on acute pain and P.major is more effective than the other. 

 
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