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Paper Information

Title: 

ANEMIA AND ITS CORRELATION WITH ERYTHROPOIETIN IN COPD

Type: SPEECH
Author(s): ATARAN D.,REZAEI TALAB F.,KHAJEH DALOUEI M.,BABAEIAN M.,REZAEI S.
 
 
 
Name of Seminar: IRANIAN CONGRESS OF PHYSIOLOGY AND PHARMACOLOGY
Type of Seminar:  CONGRESS
Sponsor:  PHYSIOLOGY AND PHARMACOLOGY SOCIETY, MASHHAD UNIVERSITY OF MEDICAL SCIENCE
Date:  2007Volume 18
 
 
Abstract: 

Introduction: Although chronic obstructive pulmonary disease COPD) traditionally associated with polycythemia, its systemic (inflammatory component can interfere with erythropoiesis and resulted in anemia of chronic disease .We determined in a group of COPD patients the prevalence of anemia and its relationship to erythropoietin and severity of disease.
Material and methods: 80 patients with mean age 66.4 +/- 11.5 FEV1 45.4 +/- 16.6% were enrolled to the study. Severity of disease was defined according to the global initiative for chronic obstructive lung disease guidelines.
Results: Anemia of chronic disease was diagnosed in 13 patients which represent a prevalence of 16.3%. Erythropoietin levels was 203 59+/- and 70.3 +/-255 U/L in anemic and nonanemic groups respectively. There was no significant difference between two groups (P= 0.264). Also there was no significant correlation between anemia and severity of disease.
Conclusion: This study documents that anemia occurs relatively frequently in COPD patients. Although erythropoietin level suppression was seen in anemia of chronic disease, there was no. significant difference between anemic and nonanemic patients .

 
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