Paper Information

Title: 

EVALUATION OF PATIENTS WITH UNKNOWN ORIGIN OF COMA ADMITTED IN I.C.U. OF LOGHMAN - HAKIM HOSPITAL POISONING CENTER

Type: SPEECH
Author(s): PAJOUMAND A.A.K.*,SHADNIA SH.,NATEGHIFARD F.
 
 *LOGHMAN HAKIM HOSPITAL POISONING CENTER, FAULTY OF MEDICINE, SHEED-BEHESHTI UNIVERSITY OF MEDICAL SCIENCES
 
Name of Seminar: IRANIAN CONGRESS OF TOXICOLOGY
Type of Seminar:  CONGRESS
Sponsor:  SOCIETY OF TOXICOLOGY
Date:  2004Volume 8
 
 
Abstract: 

The objection of this project mainly focused on clinical evaluation in all comatose patients who come in I.C.U. toxicological unit of Loghman-Hakim Hospital with unknown origin of coma.
The method of this study was case series from 850 patients in 1381 who were admitted in I.C.U. of Loghman-Hakim Hospital Poisoning Center, data sources were the records which we had in patients’ files. Those who died, we received data from Iranian Medico-Legal Organization. From 850 patients we had 88 patients with coma with unknown origin (C.O.U) with final data as bellow:
72 (81.82%) of patients finally revealed drug overdose: multi drug poisoning, 34 patients (48%); tricyclic antidepressants poisoning, 15 patients (21%); opium poisoning, 10 patients (13%); unknown drug poisoning, 7 patients (9.7%); carbamazepin poisoning, 6 patients (8.3%).7 (7.95%) of patients with central nervous system structural involvement: intracranial hemorrhage in 4 patients (57.14%), stroke in 2 patients (28.57%) and encephalitis in 1 patient (14.29%). 5 (5.68%) of patients had other organic lesions: ischemic heart disease in 3 patients (60%), hypoxia due to chocking in 1 patient (20%) and unknown hypoxia in 1 patient (20%). 4 (4.55%) patients were not shown any origin in our series.
In this study we detected that in patients with C.O.U. still drug overdose is major cause of coma; in second rank central nervous system involvement especially intracranial hemorrhage is main problem. Ischemic heart disease thought to be very common cause of sudden death but it could be misdiagnosed with drug overdose.

 
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