Paper Information

Title: 

COMPARISON OF THRESHOLD, AMPLITUDE AND LATENCY OF VESTIBULAR EVOKED MYOGENIC POTENTIAL (VEMP) IN MIGRAINE PATIENTS WITH THOSE IN NORMAL SUBJECTS

Type: PAPER
Author(s): MOALLEMI M.*,HAJI ABOLHASAN F.,FATAHI JAMILEH,ABOLFAZLI R.,JALAEI SH.
 
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Name of Seminar: INTERNATIONAL CONNGRESS OF IRANIAN SOCIETY OF OTOLARYNGYOLOGY / HEAD AND NECK SURGERY
Type of Seminar:  CONGRESS
Sponsor: 
Date:  2010Volume 1
 
 
Abstract: 

BACKGROUND AND AIM: PATIENTS WITH MIGRAINE COMMONLY SHOW VESTIBULAR SYMPTOMS. HOWEVER, EVEN IN THE ABSENCE OF VESTIBULAR SYMPTOMS, NEUROTOLOGICAL TESTS MAY BE ABNORMAL INTERICTALLY, SUGGESTING SUBCLINICAL VESTIBULAR DYSFUNCTION IN MIGRAINE. TO EVALUATE THE VESTIBULAR SYSTEM IN THESE PATIENTS, IN THIS STUDY, VESTIBULAR EVOKED MYOGENIC POTENTIALS (VEMPS) ARE ASSESSED IN TWO GROUPS, I.E. MIGRAINE PATIENTS AND NORMAL PARTICIPANTS. THE AIM OF THIS STUDY IS COMPARING VESTIBULAR EVOKED MYOGENIC POTENTIALS (VEMPS) IN MIGRAINE PATIENTS AND NORMAL PARTICIPANTS. CONSEQUENTLY, IT IS ANOTHER STEP TOWARD UNDERSTANDING VESTIBULAR CHANGES IN PATIENTS WITH MIGRAINE.
MATERIAL AND METHOD: SUBJECTS INCLUDED 25 PATIENTS WITH MIGRAINE AND 26 HEALTHY VOLUNTEERS. THE RANGE OF AGE IN PARTICIPANTS WAS 20-53 YEARS OLD. NONE OF THE SUBJECTS HAD NECK DISEASES, HEARING LOSS OR A HISTORY OF VESTIBULAR DISEASE. THE TONE BURST, (500 HZ) WITH AN INTENSITY OF 95 DB NH, RAREFACTION POLARITY AND A REPETITION RATE OF 5.1/SEC, WAS DELIVERED THROUGH AN INSERT EARPHONE AND THE VESTIBULAR EVOKED MYOGENIC POTENTIAL WAS RECORDED.
RESULTS: THE MEAN OF THE ABSOLUTE AMPLITUDE AND THRESHOLD VALUES IN MIGRAINE PATIENTS DIFFERED SIGNIFICANTLY FROM THOSE IN THE NORMAL GROUP, AND WERE LESS AND MORE IN MIGRAINE PATIENTS THAN IN THE NORMAL GROUP, RESPECTIVELY. THE P13 LATENCY MEAN WAS DELAYED IN PATIENTS COMPARED WITH IN NORMAL SUBJECTS. (P<0.05) THERE WAS NO STATISTICAL DIFFERENCE BETWEEN THE TWO GROUPS IN THE MEAN OF N23 LATENCY AND AMPLITUDE RATIO. (P>0.05)
CONCLUSION: ALTHOUGH THE TARGET PLACE OF THE CAUSAL MECHANISMS IN MIGRAINE THAT AFFECT VEMP IN CENTRAL OR PERIPHERAL VESTIBULAR STRUCTURES OR BOTH ARE NOT CONCLUSIVELY OBVIOUS, THE FINDINGS OF THE PRESENT STUDY TEND TO LEAN TOWARDS CENTRAL VESTIBULAR DISORDERS IN THIS DISEASE.

 
Keyword(s): VESTIBULAR EVOKED MYOGENIC POTENTIALS, SACCULE, VESTIBULAR SYSTEM, MIGRAINE
 
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