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Paper Information

Title: 

"A COMPARATIVE STUDY OF EFFECTIVENESS AND SAFETY OF FENTANYL,SUFENTANYL AND ALFANTANYL IN PATIENTS WHO UNDERGO ESWL"

Type: PAPER
Author(s): BABOLHAVAEGI H.,FARHANCHI A.
 
 
 
Name of Seminar: CONGREH ANJOMAN UROLOGY IRAN
Type of Seminar:  CONGRESS
Sponsor:  ANJOMAN OROLOGY
Date:  2005Volume 8
 
 
Abstract: 

PROPOSE: RENAL STONES FROM THE ANCIENT TIMES HAVE BEEN ONE OF THE MEDICAL PROBLEM FOR HUMAN. UNTILL 1980 WHEN EXTRA CORPORAL SHOCK WAVE LITHOTRIPSY (ESWL) WAS INVENTED, MOST OF PATIENTS SHOUD UNDERGO GREAT SURGICAL OPERATION. DESPITE ESWL IS A NONINVASIVE METHOD BUT ENERGY THAT REVEALED IN EXTRA AREA CAUSE PAIN WHICH IS OUT OF TOLERATING THE THERESHOLD AND NEEDS ANALGESIC DRUGS. ANALGESIC DRUGS THAT IS USED ARE NEW GENERATION OF OPIOD DRUGS BUT PREFERENCES OF THESE DRUG ARE NOT WELL KONW. OUR GOAL WAS COMPARATIVE STUDY OF ADVERS EFFECTS AND EFFICACY OF OPIOD DRUGS INCLUDING FENTANIL, ALFENTANIL AND SUFENTANIL IN PATIENT WHICH UNDERGOING ESWL.
METHODS & MATERIALS: NINETY PATIENTS WERE ENROLLED IN THIS STUDY AND DIVIDED INTO 3 GROUPS. ALL PATIENS WERE RANDOMLY ASSIGNED INTO EACH GROUP IN A BLIND MANNER. SAFETY AND EFFECTIVENESS OF EACH DRUG WERE COMPARED WITH OTHERS.
RESULTS: ANALIZING DATA SHOWS NO DIFFERENCE AMONG 3 GROUPS IN DEMOGRAPHIC. IN VIEWPOINT OF EFFICACY, TOTAL DOSE OF FENTANIL DERAMATICALY IS LESS THAN ALFENTANIL (2.6 OPPOSITE 3.6). OUR COMFORT INDEX VSA IN FENTANIL AND SUFENTANIL IS MORE THAN ALFENTANIL (3.47CM AND 3.4CM OPPOSITE 4.7CM). AVERAGE PERCEPTION DOSE IN SUFENTANIL IS LESS THAN ALFENTANIL RANGE 6.5 TIME OPPOSITE 8.3 TIME. IN GENERAL EFFECT OF FENTANIL AND SUFENTANIL IS BETTER THAN ALFENTANIL. ANOTHER INDEX THAT WE SURVEY IS ADVERS EFFECTS THAT NO SIGNIFICANT DIFFERENCE WAS SEEN AMONG 3 GROUPS. IN VIEWPOINT OF COST FENTANIL IS THE CHIPSET DRUG.
DISCUSSION & CONCLUSION: IN REGARD THAT EFFICACY OF ALFENTANIL IS LESS THAN DRUGS AND EFFECT OF FENTANIL IS PARTLY BETTER THAN SUFENTANIL AND ALSO COST EFFECTIVNESS OF FENTANIL AND SIMILARLY OF ADVERS EFFECTS AMONG 3 GROUPS WE SUGGEST USING OF FENTANIL IN FIRST LINE ANALGESIC IN PATIENT THAT UNDERGOING ESWL.

 
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