Paper Information

Title: 

MAGNESIUM HYDROXIDE IN THE TREATMENT OF URGE INCONTINENCE

Type: PAPER
Author(s): MIRZAZADEH M.*,SALEHI F.,ZARGAR M.A.
 
 *
 
Name of Seminar: CONGREH ANJOMAN UROLOGY IRAN
Type of Seminar:  CONGRESS
Sponsor:  ANJOMAN OROLOGY
Date:  2005Volume 8
 
 
Abstract: 

PURPOSE: URGE INCONTINENCE IS THE MOST COMM ON TYPE OF URINAREY IN CONTINENCE IN AGEDFFEMALE PATIENTS AND IS THE SECOND MOST COMMON TYPE IN ALL OF THE FEMALE PATIENTS.
DETRUSOR INSTABILITY IS THE MOST COMMON CAUSE OF URGE IN CONTINENCE IN PATIENTS WITHIUT ANY NEUROLOGICAL DISORDERS.
ANTICHULINERGICS AND CALCIUM CHANNEL BLOUKERS ARE THE MOST IMPORTANT DRUGS IN THE TREATMENT OF THIS DISEASE. WE EVALVATED THE EFFICACY OF MAGNESIUM HYDROXIDC IN THE TREATMENT OF URGE INCONTINENCE. MATERIALS METHODS: A TOTAL OF 60 PATIENTS WITH URGE INCONTINENCE ENROLLED IN TWO GROUPS RANDOMLY. THE GROUP 1 (30 PUTIENTS) TREATED WITH MAGNESIUM HYDROXIDE 350 MG (BID) AND THE GROUP 2 (30 PUTIENTS) TREATED WITH PLACEBO FOR 1 MONTH. A COMPLETE UROGYNECOLOGICAL STUDY, INCLUDING CLINICAL SIGNS, URINARY AND URODYNAMIC STUDIES WERE DONE IN EACH CASE AND REPEATED AFTER TREAT MENT. RESULTS: OF THE PATIENTSIN GROUP 1 40% AND IN GROUP 2 16.7% SHOWED IMPROVEMENT OF CLINICAL SIGNS.
THERE WAS STATISTICALLY SIGN FICANT DIHERENCE BETWEEN GROUPS <P<0.001).
IN GROUP 1 NOCTURIA DECREASED FROM 1.8 TO 1.3 TIMES (P<0.001), FREGUENCY DECREASED FROM 12.4 TO 10.4 TIMES (P<0.001) AND DIURNAL INCONTINENCE DECREASED FROM 2.3 TO (P<0.001) BUT IN GROUPS TERE WAS NOT ANY SIGNIFICANT DIFFERENCE IN THESE VARIABLES.
CONCLUSIONS: MAGNESIUM HYDROXIDE FOR THE TREATMENT OF URGE INCONTINENCE HAS MANG BENEFICIAL EFFECTS. THEREFORE WE RECOMMEND IT FOR THE TREAT MENT OF THIS PATIENTS.

 
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