Paper Information

Title:  THERAPEUTIC EFFECT OF FLUOXETINE IN THE TREATMENT OF PREMATURE EJACULATION (REVIEW ARTICLE AND PRESENTATION OF CASE)
Type: PAPER
Author(s): TADAYON ALI REZA*,MANSOURI DARYOUSH,AHMADI EJAZ
 
 *
 
Name of Seminar: CONGREH ANJOMAN UROLOGY IRAN
Type of Seminar:  CONGRESS
Sponsor:  ANJOMAN OROLOGY
Date:  2005Volume 8
 
 
Abstract: 

PROPOSE: TO DESCRIBE THE NEUROLOGIC AND PSYCHOLOGIC BACKGROUND, NEW HYPOTHESIS, AND PSYCHO PHARMACOTHERAPY OF PREMATURE EJACULATION.
METHODS & MATERIALS: A COMPUTERIZED MEDLINE SEARCH OF STUDIES WERE PERFORMED ON RESEARCH ON PREMATURE EJACULATION FROM 1980 T0 2002. THE STUDIES AND REPORTS WERE SUMMARIZED AN ANALYZED AND COMPARED WITH THE STUDY THAT PERFORMED BY THE AUTHOR IN BANDAR ABBAS UNIVERSITY OF MEDICAL SCIENCES. IN A PROSPECTIVE STUDY IN BANDAR ABBAS 71 CASE OF PRIMARY PE SELECTED AND TREATED BY PLACEBO, CLOMIPRAMINE AND FLUOXETINE IN 3 COURSE OF ONE MONTH DURATION.
RESULTS: RESULTS: THESE STUDIES INDICATE THAT LIFELONG RAPID EJACULATION IS A NEUROLOGIC PHENOMENON RELATED TO CENTRAL SEROTONONERGIC NEUROTRANSMISSION AND LIKELY IS A HEREDITARY FACTORS. FLUOXETINE WAS THE DRUG OF CHOICE IN THE MOST STUDIES AND OUR RESULTS SHOWED THE SAME. EJACULATION LATENCY TIME INCREASED BY FLUOXETINE MORE THAN 3.5 TIMES AND CLOMIPRAMINE MORE THAN 1.9 TIME AND PLACEBO TO 1.1 TIME.
DISCUSSION & CONCLUSION: CONCLUSION: PREMATURE EJACULATION IS A LONG LIFE NEUROLOGIC DISEASE AND FLUOXETINE IS THE DRUG OF CHOICE IN MOST CASES.

 
Keyword(s): PREMATUREEJACULATION, FLUOXETINE, CLOMIPRAMINE
 
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