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Paper Information

Title: 

ENGINEERING THE PLANT CELL GENOME FOR SECONDARY METABOLITES PRODUCTION

Type: PAPER
Author(s): RAHMANI M.,DANESHVAR M.,MOKHTARZADEH S.
 
 
 
Name of Seminar: HAMAYESHE MANTAGHEI KARBORD FANAVARIHAYE NOVIN DAR KESHAVARZI
Type of Seminar:  CONGRESS
Sponsor:  Islamic Azad University, Shiraz
Date:  2008Volume 1
 
 
Abstract: 

PLANT SECONDARY METABOLISM IS VERY IMPORTANT FOR TRAITS SUCH AS COLOR AND FLAVOR OF FOOD, AND RESISTANCE AGAINST PESTS AND DISEASES. MOREOVER, IT IS THE SOURCE OF MANY CHEMICAL PRODUCTS SUCH AS DRUGS, FLAVORS AND FRAGRANCES. POSSIBILITY OF ENGINEERING THE SECONDARY METABOLITE PATHWAYS OF THE PLANT CELL FACTORY IN ORDER TO PRODUCE MORE OF A FINE CHEMICAL, PRODUCE LESS OF A TOXIC COMPOUND, OR EVEN TO MAKE NEW COMPOUNDS, IS FEASIBLE NOWADAYS, BUT IT REQUIRES KNOWLEDGE OF THE BIOSYNTHETIC PATHWAYS INVOLVED. TO INCREASE SECONDARY METABOLITE PRODUCTION DIFFERENT STRATEGIES CAN BE FOLLOWED, SUCH AS OVERCOMING RATE LIMITING STEPS, REDUCING FLUX THROUGH COMPETITIVE PATHWAYS, REDUCING CATABOLISM AND OVER EXPRESSION OF REGULATORY GENES. FOR THIS PURPOSE NOT ONLY GENES OF PLANT ORIGIN CAN BE OVER EXPRESSED, BUT ALSO MICROBIAL GENES HAVE BEEN USED SUCCESSFULLY. OVER EXPRESSION OF PLANT GENES IN MICROORGANISMS IS ANOTHER APPROACH; WHICH MIGHT BE OF INTEREST FOR BIOCONVERSION OF READILY AVAILABLE PRECURSORS INTO VALUABLE FINE CHEMICALS.

 
Keyword(s): METABOLIC ENGINEERING, PLANT SECONDARY METABOLISM, PLANT CELL
 
 
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