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Paper Information

Title: 

THE EFFECTS OF THE ETHANILIC EXTRACT OF NIGELLA SATIVA SEEDS ON KIDNEY STONES IN RABBIT

Type: POSTER
Author(s): MOHAMMADIAN N.*,HAJZADEH M.A.R.,RAHMANI Z.
 
 *DEPT. OF PATHOLOGY, GHAEM HOSPITAL, MUMS, MASHHAD, IRAN
 
Name of Seminar: IRANIAN CONGRESS OF PHYSIOLOGY AND PHARMACOLOGY
Type of Seminar:  CONGRESS
Sponsor:  PHYSIOLOGY AND PHARMACOLOGY SOCIETY, MASHHAD UNIVERSITY OF MEDICAL SCIENCE
Date:  2007Volume 18
 
 
Abstract: 

The incidence of urinary stones is very high in population. Treatment of patients with kidney stones in primary stages can reduce the side effects and may reduce the surgical operations and postoperative complications.
The aim of this study is to investigate the effects of the ethanolic extract of N.S seeds on kidney stones in rabbit. In this study 24 rabbits were divided into 4 groups. Group A as intact control was received tap drinking water for thirty days. Group B (ethylene glycol control), groups C and D as experimental animals all were received 1% ethylen glycol in drinking water for 30 days. Furthermore groups C and D were also treated with 250mg/kg. B.W N.S extract from respectively the first and the 15th day through the end of the experiment. After 30 days all kidneys were removed and sections were prepared with routine histological techniques, slides were examined under light microscope to evaluate calcium oxalate crystals. The results showed that the number of calcium oxalate deposits were not significantly different in group B vs A (P>0.05). Therefore; it may be concluded that rabbit is not a proper model for kidney stone investigation.

 
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