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Paper Information

Title: 

A COMPARISON EFFECT OF INDOMETACIN AND CHICHORY EXTRACT ON TUBULAR EXCRETION OF PHENOL RED

Type: POSTER
Author(s): JAVID DASHT BAYAZ J.,SHEKARIAN M.H.,NAJAFZADEH VARZI H.
 
 
 
Name of Seminar: IRANIAN CONGRESS OF PHYSIOLOGY AND PHARMACOLOGY
Type of Seminar:  CONGRESS
Sponsor:  PHYSIOLOGY AND PHARMACOLOGY SOCIETY, MASHHAD UNIVERSITY OF MEDICAL SCIENCE
Date:  2007Volume 18
 
 
Abstract: 

Use of chichony for treatment of goats has been explained, thus, in this study effect of indometacin and chichory on tubular excretion of phenol red in rats was compared.
In group 1, phenol red was injected intravenously; then, their serum concentration was measured after 30, 60, 180 min, by spectrophotometer. In group 2, hydroalcholic extract of chichory leaves was injected intrapritonealy. In group 3, indometacin was orally administrated. Then, phenol red was injected and measured as group 1. The mean of phenol red concentration in serum of group 2 was increased. In comparison to group 1. this effect was not seen by indometacin group 3. Thus, chichory may competitate with phenol red and decrease its tubular active excretion and chichory many uricosuric effect.

 
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