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Paper Information

Title: 

IN VITRO TRANSDIFFERERNTIATION OF RAT MESENCHYMAL STEM CELLS INTO INSULIN-PRODUCING CELLS

Type: POSTER
Author(s): NESHAT Z.,MOGHADAM MATIN M.,BAHRAMI A.R.,MOGHIMI A.
 
 
 
Name of Seminar: IRANIAN CONGRESS OF PHYSIOLOGY AND PHARMACOLOGY
Type of Seminar:  CONGRESS
Sponsor:  PHYSIOLOGY AND PHARMACOLOGY SOCIETY, MASHHAD UNIVERSITY OF MEDICAL SCIENCE
Date:  2007Volume 18
 
 
Abstract: 

Stem cell therapy is one way for treatment of diabetes disease. In this case, we can use stem cells which can renew themselves and can differentiate into insulin producing cells. In present study we used mesenchymal stem cells (MSCs) extracted from bone marrow of Wistar rats. Mesenchymal stem cells are multipotent stem cells which can differentiate into mesenchymal tissue progeny, such as osteocytes, chondrocytes, adipocytes, tendon and muscle. These cells were cultured under inducing conditions to insulin-producing cells. Differentiation of these cells was proved by dithizone staining (DTZ) and immunocytochemistry for C-peptide.

 
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