Paper Information

Title: 

COMPARISON OF EFFECT OF FISH OIL CONTAINING DIET WITH DIET CONTAINING IRANIAN FAT CONSUMPTION PATTERN, AND STANDARD DIET, ON PREGNANCY INDICES, GROWTH AND NEURODEVELOPMENT IN RAT

Type: POSTER
Author(s): MOHAMMAD SHIRAZI M.,SABET KASAEI M.,TALEBAN F.A.,ABADI A.,VAFA M.
 
 
 
Name of Seminar: IRANIAN CONGRESS OF PHYSIOLOGY AND PHARMACOLOGY
Type of Seminar:  CONGRESS
Sponsor:  PHYSIOLOGY AND PHARMACOLOGY SOCIETY, MASHHAD UNIVERSITY OF MEDICAL SCIENCE
Date:  2007Volume 18
 
 
Abstract: 

Objective: The present study was designed to evaluate the effects of a fish oil containing diet on pregnancy indices, growth and neurodevelopment of rat from fetal period until puberty.
Methods: 30 female Wistar rats were fed three different diets: the standard diet contained soybean oil, another diet contained fish oil and the third one contained a mixture of milk butter, Hydrogenated cotton seed oil and sunflower oil which was similar to Iranian fat consumption pattern, during pregnancy and lactation. Their pups were also weaned onto the same diet until puberty. Pregnancy indices in dams, growth and developmental indices in pups were assessed. Mean of indices were calculated using SPSS software, and compared with ANOVA.
Results: Neurodevelopmental indices (crawling & posture normalization) occurred 2 days earlier in soy bean oil-fed animals while physical development indices (fur development, eye & ear opening) happened one day earlier in fish oil-fed pups. Other indices were similar among groups.
Conclusion: Earlier occurrence of neurodevelopmental indices in soy bean oil-fed animals may be due to existence of precursors of both omega-3 and omega-6 fatty acids in soybean oil. Earlier occurrence of physical development indices in fish oil-fed pups may be due to effect of long chain omega-3 fatty acids in placental blood flow enhancement which improves physical development.

 
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