Paper Information

Title: 

EFFECT OF DIFFERENT DURATIONS EXERCISE IN SPECIAL TIME ON SPATIAL LEARNING AND LONG-TERM MEMORY IN RATS

Type: POSTER
Author(s): ALAEI H.A.,MOLOUDI R.A.,SARKAKI A.R.,AHMADI A.
 
 
 
Name of Seminar: IRANIAN CONGRESS OF PHYSIOLOGY AND PHARMACOLOGY
Type of Seminar:  CONGRESS
Sponsor:  PHYSIOLOGY AND PHARMACOLOGY SOCIETY, MASHHAD UNIVERSITY OF MEDICAL SCIENCE
Date:  2007Volume 18
 
 
Abstract: 

Introduction: A number of previous studies have considered this fact that exercising has beneficial effects on different parts of brain, synapses, hippocampal neurogenesis, neuronal activity, synaptic structure, enhancement of neurotransmitters and spatial memory.
Methods: Four rat groups were included as follows: control, exercise40 (30 days before and 8 days exercise during the Morris water maze testing period), exercise 30 (30 days exercise before the Morris water maze testing period) and exercise 8 (8 days exercise only during the Morris water maze testing period). Spatial memory and long-term memory was recorded in the Morris water maze during 8 days. The data obtained from our experiments was analyzed, Two-way ANOVA test.
Results: showed a considerable increase in total means of eight day long-term memory among three exercise groups and in comparison with control group (p<0.05). Comparing the results between exercise groups and control group, we found a significant improve in exercise 40 (p<0.01) and exercise 30 (p<0.05).
Discussion:  Our results confirmed the hypothesis that longer period of exercise will have progressive and improving effects spatial memory. Long-term memory is more affected by simultaneous exercise with spatial memory tests, rather than periods or previous exercise. This should be related to the fact that, different periods of exercise can influence different pathways in cells. For instances short-term exercise increased mRNAs synapsin I. long-term exercise increased MAPK 1, 2, neurotransmitter and vesicular transferring protein.

 
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