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Paper Information

Title: 

THE EFFECT OF RAPHE MAGNUS IRREVERSIBLE INACTIVATION AND NITRIC OXIDERGIC NEURONS ON SKIN BLOOD VESSELS IN RESPONSE TO HYPOTHERMIA IN MALE RATS

Type: POSTER
Author(s): KOUROSH ARAMI M.,HAJIZADEH S.,KHOUSHBATEN A.,SARIHI A.A.R.
 
 
 
Name of Seminar: IRANIAN CONGRESS OF PHYSIOLOGY AND PHARMACOLOGY
Type of Seminar:  CONGRESS
Sponsor:  PHYSIOLOGY AND PHARMACOLOGY SOCIETY, MASHHAD UNIVERSITY OF MEDICAL SCIENCE
Date:  2007Volume 18
 
 
Abstract: 

It has been shown that Nucleus Raphe Magnus (NRM) can affect on thermoregulatory process. In this study we examined the effect of NO level changes in NRM on mechanisms that are involved in skin blood flow regulation.
In this study after cannulation above the NRM by injection of lidocaine, L-NAME and SNP, we measured tail blood flow by laser dopler to evaluate the effect of nitric oxidergic nourones on blood flow regulation. Our results indicated that tail blood flow decreased by hypothermia and SNP injection but it increased after lidocaine and, L-NAME injection. It is concluded that probably NO released from nitric oxidergic nourons through effect on raphe serotonergic nourons cause more reduction in peripheral blood flow in hypothermia.

 
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