Paper Information

Title: 

THE EFFECTS OF HIGH FAT INTAKE ON SERUM LIPIDS AND ATHEROSCLEROSIS INDICATORS IN BROILER CHICKENS AS AN ANIMAL MODEL

Type: POSTER
Author(s): VAHDATPOUR T.*,TESHFAM M.,GHIASI J.
 
 *DEPT. OF ANIMAL SCIENCE-PHYSIOLOGY, FACULTY OF AGRICULTURE, AZAD ISLAMIC UNIVERSITY OF SHABESTAR
 
Name of Seminar: IRANIAN CONGRESS OF PHYSIOLOGY AND PHARMACOLOGY
Type of Seminar:  CONGRESS
Sponsor:  PHYSIOLOGY AND PHARMACOLOGY SOCIETY, MASHHAD UNIVERSITY OF MEDICAL SCIENCE
Date:  2007Volume 18
 
 
Abstract: 

Introduction: On the basis of quality and quantity of serum lipids and the basic site of fatty acids synthesis (liver), broiler chickens are very similar to human. Therefore broilers can be used as animal model for researches on human.
Methods: This experiment was conducted to determine the effects of increasing energy to protein and energy to other nutrients materials ratio in the diet, on serum lipids and atherosclerosis indicators in broiler chickens. With addition of three types of fats in two levels (4 and 8%) to basal diet that were already balanced on National Research Council (NRC) recommendations, seven different non-isonitrogenic and non-isocaloric diets were provided and given adlibitum. At 35 and 49 days of ages, blood samples were collected from wing vein and then by using Autoanalyser (ALCYON 300) sera were analyzed.
Results: Serum lipids concentrations including total cholesterol, triglycerides, HDL, LDL, VLDL and atherosclerosis indicators including LDL/HDL and T-CHOL/HDL had no significant difference in between dietary treatment groups. Serum LDL concentration and LDL/HDL indicator showed significant elevation from 35 to 49 d (p<0.01), whereas serum Cholesterol concentration showed decline at the same times (p<0.05). With increasing dietary fat level from 4 to 8%, serum Cholesterol level showed significant increase (p<0.05).
Conclusion: Broiler chickens, probably because of some physiological resistance systems, like over compensation (down regulation of lipoprotein lipase) are more resistant against the high dietary fat intake.

 
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