Paper Information

Title: 

THE EFFECT OF TEA (CAMELLIA THEA L.) ON ACCELERATION OF ACETAMINOPHEN’S EFFECTIVENESS IN HEADACHE

Type: POSTER
Author(s): ZANGIABADI H.*,SAHRAEI HEDAYAT,HOJAT M.
 
 *DEPARTMENT OF PHYSIOLOGY, SCHOOL OF MEDICINE, SHAHEED BEHESHTI UNIVERSITY OF MEDICAL SCIENCES
 
Name of Seminar: IRANIAN CONGRESS OF PHYSIOLOGY AND PHARMACOLOGY
Type of Seminar:  CONGRESS
Sponsor:  PHYSIOLOGY AND PHARMACOLOGY SOCIETY, MASHHAD UNIVERSITY OF MEDICAL SCIENCE
Date:  2007Volume 18
 
 
Abstract: 

Introduction: Headache is the most common complaint in patients. In order to alleviate the headache, specialists have recommended different chemical and non-chemical drugs. Acetaminophen is one of the widespread analgesic drugs used for headache relief and tea also is the most common drink for the most people around the world. Tea’s alkaloids seem to accelerate the acetaminophen metabolism. The present study aims to assess the effect of tea consumption on effectiveness of acetaminophen.
Method: In order to test the hypothesis, 120 patients suffered from headache referred to the Shaheed Motahari general hospital in Jahrom were requested to take part in a single blind clinical trial study. 52 patients as the case group have received tea and after 60 min they had taken a 365 mg acetaminophen tablet (the experimental group). While, 68 patients as the control group received a glass of warm water and 60 min later had the same drug. Pain intensity was twice measured by a self-report questionnaire. The first one was 30 min before the tea or water consumption and the second, 90 min after receiving the acetaminophen.
Results: Results showed that:
consumption of tea before taking the acetaminophen significantly reduced the pain intensity comparing with the control group. In addition, with respect to sex and age, no significant differences were found between the groups.
Conclusion: It can be concluded that consumption of tea before taking acetaminophen may accelerate the effects of the drug.

 
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