Paper Information

Title:  THE PROPHYLACTIC EFFECT OF NIGELLA SATIVA ON ASTHMA DISEASE
Type: POSTER
Author(s): JAVAN H.*,BOSKABADI M.H.,SAJADI M.,RAKHSHANDEH H.
 
 *DEPARTMENT OF PHYSIOLOGY, GHAEM MEDICAL CENTRE, MASHHAD UNIVERSITY OF MEDICAL SCIENCES, MASHHAD, IRAN
 
Name of Seminar: IRANIAN CONGRESS OF PHYSIOLOGY AND PHARMACOLOGY
Type of Seminar:  CONGRESS
Sponsor:  PHYSIOLOGY AND PHARMACOLOGY SOCIETY, MASHHAD UNIVERSITY OF MEDICAL SCIENCE
Date:  2007Volume 18
 
 
Abstract: 

Background: In this study, the prophylactic effect of the boiled extract of Nigella sativa on asthmatic disease was examined.
Methods:
Twenty nine asthmatic adults were randomly divided into control group (14 patients) and study group (15 patients) and were studied for 3 months. In study group 15ml/kg of 2g% boiled extract daily and in control group a placebo solution was administrated throughout the study. Asthma symptom score and wheezing were recorded at the beginning, middle and at the end of the study. Pulmonary function tests (PFTs) were also measured and the drug regiment of the patients was evaluated at three different visits.
Results: All asthma symptoms, frequency of asthma symptoms/week, chest wheezing and pulmonary function test (PFT) values in study group, were significantly improved in second and third visits  than on the first visit (p<0.05 to p<0.001). In addition, further improvement in chest wheezing and severity of disease on the third visit were compared to the second visit in this group (p<0.05 for both cases). In the second and third visits all symptoms in the study group improved and were significantly different than the control group (p<0.05 to p<0.001). However, in control group, there were only small improvements in some parameters in just the second visit. The usages of different types of drugs in the study group were decreased at the end of the study.
Conclusion:  In conclusion, the results of the present study showed that Nigella sativa has an prophylactic effect on asthma disease.

 
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