Paper Information

Title:  EFFECT OF ACUTE SUPPLEMENTATION OF VITAMIN C ON EXERCISE-INDUCED LIPID PEROXIDATION AND MUSCLE DAMAGE
Type: POSTER
Author(s): NOKHOSTIN ROUHI B.*,RAHMANINIA FARHAD,BABAEI PARVIN,BOHLOULI SH.
 
 *GUILAN UNIVERSITY, IRAN
 
Name of Seminar: IRANIAN CONGRESS OF PHYSIOLOGY AND PHARMACOLOGY
Type of Seminar:  CONGRESS
Sponsor:  PHYSIOLOGY AND PHARMACOLOGY SOCIETY, MASHHAD UNIVERSITY OF MEDICAL SCIENCE
Date:  2007Volume 18
 
 
Abstract: 

Introduction: Oxygen free radicals are highly reactive species that are produced in increased quantities during strenuous exercise and can damage critical biological targets such as membrane phospholipids. The purpose of this study was to examine the effect of acute ascorbic acid supplementation on exercise-induced free radical production in healthy subjects.
Methods: Sixteen healthy male, unfamiliar with the exercise protocol, randomly received either antioxidant (AO) (1000 mg vitamin C) or placebo (P) 2 hours before a 30-min treadmill run at 75% Vo2max.
Results: Plasma vitamin C concentration increased significantly 2 hour after supplementation, immediately and 2 hour after exercise in AO group(P<0.05). Serum Creatine kinase, increased significantly after exercise (P<0.05) and decrease 24 h after exercise in both groups. Malondealdehyde increased significantly after exercise in P group (P<0.05) but not in AO group (P>0.05).
Conclusion: The results indicate that acute ascorbic acid supplementation prevented exercise-induced oxidative stress but not muscle damage in these subjects.

 
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