Paper Information

Title: 

VALUATION OF CARROT SEED EXTRACT ON THE SPERMATOGENESIS OF WISTAR RAT

Type: SPEECH
Author(s): NOURI M.,KHAKI A.,FATHIAZAD -
 
 
 
Name of Seminar: IRANIAN CONGRESS OF PHYSIOLOGY AND PHARMACOLOGY
Type of Seminar:  CONGRESS
Sponsor:  PHYSIOLOGY AND PHARMACOLOGY SOCIETY, MASHHAD UNIVERSITY OF MEDICAL SCIENCE
Date:  2007Volume 18
 
 
Abstract: 

In ancient medicine the benefit effect of carrot and its seeds, on the impotency of the males has been mentioned. Hakim sayed Esmail jorjani has been written in carrot chapter of zakhire kharazmeshah: the carrot increase the impotency and its seeds reveals to be more powerful, and wild carrot being more effective in men, but in female it has antifertility effect. The study designed to determine spermatogenesis carrot seed extract (CSE) on the spermatogenesis and plasma levels of LH, FSH and testosterone. 40 wistar male rats were divided in to five groups, o (control), 200, 400 and 400 (+5mg/kg gentamycin) mg/kg/day CSE intraperitonaly injected in group 1, 2, 3 and 4 for 4 weeks, respectively. The group 5 received only 5 mg/kg/day gentamycin intraperitonaly. After 24 days blood sample were collected and testis separated from the animal and weighted and number of the sperm in the homogenate of testis counted. The results were evaluated nonparametically methods The results showed injection of CSE causes significant increase in the concentration of sperms (P<0.00) while it had no effect on the vitality and motility of the sperms (P>0.05). Increase dose of the CSE had no meaningful effect on the mentioned parameters. However 400 mg/kg/day of the CSE protect spermatogenesis from the inhibitory effect of gentamycin. Significant increase in the plasma levels of LH and testosterone were observed in the third group. In addition CSE prevents the negative effect of antibiotic on the production of the sex hormones and no marked differences in the serum levels of testosterone and LH were noticed between first and fifth groups.

 
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