Paper Information

Title: 

EVALUATION OF THE EFFECT OF ATROPINE ON FRIEDMAN CURVE IN ACTIVE PHASE PRIMIPARUS WOMEN

Type: SPEECH
Author(s): DEHGHANI FIROUZABADI R.,TAYEBI N.
 
 
 
Name of Seminar: IRANIAN CONGRESS OF PHYSIOLOGY AND PHARMACOLOGY
Type of Seminar:  CONGRESS
Sponsor:  PHYSIOLOGY AND PHARMACOLOGY SOCIETY, MASHHAD UNIVERSITY OF MEDICAL SCIENCE
Date:  2007Volume 18
 
 
Abstract: 

Objective: This project has been designed for the effects of Atropine on improving dilatation of cervix and promoting the progression of labor course in active phase primiparus women has been referred during 1 year.
Methods: In this study that was randomized clinical trial, 200 pregnant primiparus women were divided into two groups. 100 normal primiparae were assigned into Atropine group (group 1) and placebo group (group 2) randomly. 1cc i.v. Atropine and Placebo was given the both groups in active phase. Finally, the effect of atropine was evaluated on Friedman curve, improving dilatation of cervix and promoting the progression of labor course. The statistical analysis was done by T Test, X2 and Fisher exact test.
Results: The mean time period from drug administration to full dilation of the cervix was 2.05 h in group 1 and 2.39 h in group 2. (P<001) Also, the mean time period of labor was 4.96 h in group 1 and 6.12 h in group 2. Cesarean delivery in group 1 and group 2 was 3% and 9% respectively. 49% of them in group 1 complained of thirst and 29% had increased heart rate and 1% woman complained of urinary retention and there were no obvious side effects in 21% women.
Conclusion: Not only can Atropine decrease active phase of labor but also it can decrease the rate of cesarean.

 
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