Paper Information

Title: 

CHANGES IN HEMATOLOGICAL AND BIOCHEMICAL PARAMETER OF SHEEP BLOOD WITH KETOPROFEN INJECTION

Type: POSTER
Author(s): SAMI M.,NAZEM M.N.
 
 
 
Name of Seminar: IRANIAN CONGRESS OF PHYSIOLOGY AND PHARMACOLOGY
Type of Seminar:  CONGRESS
Sponsor:  PHYSIOLOGY AND PHARMACOLOGY SOCIETY, MASHHAD UNIVERSITY OF MEDICAL SCIENCE
Date:  2007Volume 18
 
 
Abstract: 

Anti inflammatory drugs have different effects on body system and high potential to make adverse effects.
Methods: In this study 10 sheep with equal age and weight were selected and divided in control and test groups. Before the start of experiment, two blood samples were taken and the mean values were considered as pretest ones. In test group 3.3mg/kg ketoprofen was injected for 3 consecutive days. Blood samples were collected from the first until the third post test days. The results were analyzed with statistical test (one way ANOVA and Duncan's test).
Results: In test group BUN, Cholesterol, Glucose, Sodium and Potassium were increased but BUN, Glucose and Cholesterol were significant (p<0.05). In blood picture the RBC were increased significantly by 33.8% (p<0.05). Total WBC were decrease not significantly (p>0.05).
Conclusion: Because of increasing some tested factors, this drug should be used with recommended dosage in short time especially in the animal with dehydration and kidney diseases.

 
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