Paper Information

Title: 

EFFECT OF CORUCCUS SATIVUS ETHANOLIC EXTRACT ADMINISTRATION IN VENTRICULAR BRAIN OF RAT ON FEAR BEHAVIOR

Type: POSTER
Author(s): KERAMATI K.,VAEZI GH.H.,ETEMADI L.,TORKAMANI NOUGHABI M.
 
 
 
Name of Seminar: IRANIAN CONGRESS OF PHYSIOLOGY AND PHARMACOLOGY
Type of Seminar:  CONGRESS
Sponsor:  PHYSIOLOGY AND PHARMACOLOGY SOCIETY, MASHHAD UNIVERSITY OF MEDICAL SCIENCE
Date:  2007Volume 18
 
 
Abstract: 

Many reports in folk medicine said that Coruccus sativus has developmental therapeutic effects on neurvus system and psychedelic effect. Coruccus sativus named one of plants benefit economical in IRAN.
Material and Method: In this investigation we used ethanolic extract from flower's stigma and asses effect on fear behavior .Animals (Wistar) treatment with administration extract in ventricular brain by 50, 100, 200, 400 (μg/rat), harmalin drug (50μg/rat) positive control and salin for control (in each groups n>7). For fear behavior assessment used Elevated Plus-Maze apparatus. Results: showed i.c.v injection of 200, 400 (μg/rat) in comparision with control group increased fear (p<0.05). Meanwhile have not any significant difference between all doses with positive control.
Discussion: Final this study confirme effective of ethanolic extract Coruccus s. On fear behavior. In order to we suggest more study for recognition functional mechanism in next work.

 
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