Paper Information

Title: 

STUDY ON EMOTIONAL BEHAVIORS ON THE FIRST GENERATION OF MORPHINE ADDICTED MICE

Type: POSTER
Author(s): MAHMOUDIAN A.R.,BOROUSHAKI M.T.,MOGHIMI A.
 
 
 
Name of Seminar: IRANIAN CONGRESS OF PHYSIOLOGY AND PHARMACOLOGY
Type of Seminar:  CONGRESS
Sponsor:  PHYSIOLOGY AND PHARMACOLOGY SOCIETY, MASHHAD UNIVERSITY OF MEDICAL SCIENCE
Date:  2007Volume 18
 
 
Abstract: 

Introduction: In previews studies about the morphine addiction, it was shown that morphine decreases the glicocanjogation of the cell's surface in different spermatujenz stages and also increases fatality, decreases the weight and embryonic period and increases the number of addicted mice and also because of the harmonic changes in pregnancy period that affects behavioral properties on next generation, it needs to have more studies about the probable behavioral effects on offspring and addicted parents.
Methods: After addicting mice, a behavioral study on 2-month age offspring was carried out by Elevated Plus Maz and Open Field method.
Result: EMP test showed that male offspring of addicted parents are less enthusiastic to control open arm, but female offspring spend more time in close arm to decrease the stress and increase the security ratio. In Open Field method, by comparison between male offspring of addicted and none-addicted parents and male children of addicted mothers, could be shown that the washing time has increased in addicted parents' children in compare with the two other groups. Female children of none-addicted parents and addicted mothers are different in two important factors; the number of standing and washing time.
Conclusion: What became clear in OF test result is that the wide behavioral change is happened in male and female offspring of addicted parents in compare with the other groups. But the most important thing is the effects of addicted parents on female children.

 
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