Paper Information

Title: 

THE LAST FINDINGS FOR TREATMENT OF BIRD FLU

Type: POSTER
Author(s): FATHI B.,MALEKZADEH S.,MAHMOUDI GHARAEI A.
 
 
 
Name of Seminar: IRANIAN CONGRESS OF PHYSIOLOGY AND PHARMACOLOGY
Type of Seminar:  CONGRESS
Sponsor:  PHYSIOLOGY AND PHARMACOLOGY SOCIETY, MASHHAD UNIVERSITY OF MEDICAL SCIENCE
Date:  2007Volume 18
 
 
Abstract: 

In the past few years by the threat of a possible human influenza pandemic the prevention and treatment of this disease has been found a crucial value. In this review, we try to explore the last pharmacological treatment findings. There is a general agreement that the currently available arsenal of avian flu vaccines is far from perfect. The most effective and branded drug for treatment of bird flu is called "Tami flu" (Oseltamivir phosphate), a virus neuraminidase inhibitor which prevents movement of virus to come out after access to inside host cells. The process of producing Tami flu takes almost 12 months and has several steps. Its start with a plant called "Star anise" which catalysis chemical reactions. This plant grows only in some parts of Japan and China in definite season. The limitation of growing and harvesting of this plant affect producing of Tami flu directly. Recently researchers by use of genetic engineering try to find an alternative mater. According to some reports they reach to some successful steps to produce this substitute. Another new drug which is called "T-705" has been synthesized as an alternative for Tami flu if the virus resist to it or the virus mutate and make it ineffective. The necessary time to produce T-705 is about three months. This drug is an inhibitor of RNA polymerase that prevents reproduction of virus. It should be noted that there is limited publications about this drug.
Finally; these days researchers try to encourage patient’s immune system by use of serum which is provided from recover patients.

 
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