Paper Information

Title: 

THE STUDY OF HYDROALCOHOLIC EXTRACT OF OCIMUM BASILICUM ON BLOOD GLUCOSE OF DIABETIC RATS

Type: POSTER
Author(s): MAHMOUDI M.,SHAHIDI S.
 
 
 
Name of Seminar: IRANIAN CONGRESS OF PHYSIOLOGY AND PHARMACOLOGY
Type of Seminar:  CONGRESS
Sponsor:  PHYSIOLOGY AND PHARMACOLOGY SOCIETY, MASHHAD UNIVERSITY OF MEDICAL SCIENCE
Date:  2007Volume 18
 
 
Abstract: 

Introduction: Ocimum Basilicum (O.B), which is wide spread in all parts, is a native plant in our country. In traditional medicine the useful effects of it are to human disease was mentioned. The aim of this study is to find out the effect of hydroalcoholic extract of O.B on blood glucose of diabetic rats.
Methods: Fresh leaves of O.B were dried in dark. After keeping in 70% alcohol it was filtered and dried by using rotary in 50oC. This pouder was solutes in saline and three doses of it (200,400,600 mg/kg) was injected i.p to the normal and diabetics rats. After one hour by using Glucomen apparatus the blood glucose was measured.
Results: The rats were diabetic by injecting Alloxan. Acute injection of each dose shows significant decreased in blood glucose but there is no significant difference in blood glucose of three groups which were received extract. Injecting, 400mg/kg of O.B extract causes no significant difference between normal and saline received rats.
Conclusion: This study shows that, O.B extract has no effect on blood glucose of normal rats but in diabetics rats decreased it. Therefore, it is possible that O.B extract can decrease blood glucose in diabetic pati

 
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