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Paper Information

Title: 

THE EFFECTS OF PIPERINE (BLACK PEPPER ALKALOID) ON HUMAN SPERM PARAMETERS; AN IN VITRO STUDY

Type: POSTER
Author(s): YAGHOUBI E.,SAYAHI Z.,JOURSARAEI S.GH.A.,FARSI M.,MOHAMMADINIA A.A.
 
 
 
Name of Seminar: IRANIAN CONGRESS OF PHYSIOLOGY AND PHARMACOLOGY
Type of Seminar:  CONGRESS
Sponsor:  PHYSIOLOGY AND PHARMACOLOGY SOCIETY, MASHHAD UNIVERSITY OF MEDICAL SCIENCE
Date:  2007Volume 18
 
 
Abstract: 

Introduction: The compounds of some medicinal plants and some food additives have presented different effects on sperm parameters particularly its motility. Black pepper as a medicinal plant has been used as food additive. In vitro effect of piperine the alkaloid of black pepper was investigated on human sperm parameter.
Methods: Sixteen human semen samples were obtained from the local hospital. Then the samples were swim up by Ham’s f10. The samples were divided into five groups: no treatment, vehicle group, and other three samples (0.9ml) were treated by 0.1ml of piperine (0.5, 0.1, and 0.2% concentration). Sperm motility, grading and morphology parameters were assessed using light microscope at 0, 2 and 4, 8 hrs after treatment.
Results: Dose and time-dependent increases in motility accompanied by concomitant decrease in grading III and IV were noticed. These effects were significantly predominant with piperne high doses.
Conclusion: These data indicate that some exhibits a higher percentage of motility and improvement in sperm grading when piperine is added to semen fluid. According to the results it would be concluded that piperine can induce the positive effects on sperm parameters.

 
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