Paper Information

Title: 

HYPOTHALAMIC-PITUITARY-GONADAL AXIS RESPONSES OF THE MALE RATS SHORT AND LONG TIME ALTERNATIVE MAGNETIC FIELDS (50 HZ) EXPOSURE

Type: POSTER
Author(s): AHANGARPOUR A.,FATHI MOGHADAM H.,TAHMASBI BEYRGANI M.J.,SHAHBAZIAN H.,BADAVI M.
 
 
 
Name of Seminar: IRANIAN CONGRESS OF PHYSIOLOGY AND PHARMACOLOGY
Type of Seminar:  CONGRESS
Sponsor:  PHYSIOLOGY AND PHARMACOLOGY SOCIETY, MASHHAD UNIVERSITY OF MEDICAL SCIENCE
Date:  2007Volume 18
 
 
Abstract: 

Electromagnetic fields are associated with the production, transmission, and use of electricity; thus the potential for human reproductive system exposure is very high. This study was to investigate the effects of alternative MF exposure on the secretion of hypothalamic-pituitary-gonadal axis in the male rats during short and long time exposed to AMFs (50 Hz). Experiments have been done in four protocols. Each protocol included four groups (Wistar male rats, same range of age and weight) and each group contains 12 rats.  After one-week adaptation they placed in exposure to AMF (0, 25, 50 and 100 µT) for 5 hours daily for 17 or 34 days. All of protocols were started from 9:00 a.m. After experiments animals were anaesthetized, their blood has collected. Their serums were removed and kept frozen under -20oC until use. Hormones testosterone, FSH and LH were measured using gamma counter equipment with IRMA and RIA methods. The results were analyzed by one way-ANOVA statistical method (p<0.05). Chronic exposures (5h/day for 34 days) to AMFs have no effect on serum testosterone and LH. But, these AMFs induces a increase of serum FSH levels100 µT, vs. sham, 25 and 50 µT. Increased FSH suggests damage to the seminiferous tubules. In contrast, Subchronic AMFs (5 h/day for 17 days) induces a decrease of serum testosterone sham, vs 25, 50 and 100 µT. But these AMFs have no effect on serum LH and FSH levels.Our results suggest that AMFs probably causes dysfunction in gonadal axis at the hypothalamic-pituitary level in male rats in different protocols.

 
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